Therapeutic Potential of Cancer Vaccine Based on MHC Class I Cryptic Peptides Derived from Non-Coding Regions
MHC class I molecules display intracellular peptides on Sit Stand Mats cell surfaces to enable immune surveillance under pathological conditions.The source of MHC class I antigens responsible for cancer protection is not fully understood.Here, we explored the MHC class I peptidome in mouse colon cancer cells using a proteogenomic approach.We showed